Market-ready pharmaceuticals through toxicologic pathology testing


New pharmaceuticals, such as medicines and vaccines, have to be thoroughly tested for end-user safety and side effects before they can be brought to market. The science of toxicologic pathology has the designated professionals to effect such testing. By identifying pathological changes caused by certain chemicals, a toxicologic pathologist assesses chemical, vaccine and pharmaceutical safety. The pathologist can then verify whether these observed changes are pathologically relevant. The standard procedure for accomplishing this consists of studying animal testing results to extrapolate the expected effects in human application. Extensive expertise and scientific diligence are vital for correctly interpreting the results of such a safety assessment. When conducting toxicologic pathology testing, many variables must be taken into account: species, anatomy, drug class, organ weight changes and many, many more.

Ensure your pharmaceuticals are safe for use with toxicologic pathology

European and global guidelines for market access of pharmaceuticals mandate thorough safety assessments. Lax or no toxicologic pathology testing has resulted in various disasters in the past, with both the environment and human beings suffering the consequences. Debacles, such as thalidomide being widely distributed to pregnant women resulting in birth defects, have taught a hard lesson. In the far more strictly regulated market of today, pharmaceuticals already on the market are still occasionally withdrawn from shelves because of previously unknown side effects arising in human use. Employing toxicologic pathologists is thus still as vital as it has ever been. In this manner, you ensure pharmaceuticals slated for release are proven safe beforehand.

Decades of expertise in one reliable lab

For a laboratory led by an experienced and certified pathologist, look no further than Global Pathology Support in the Netherlands. This lab is your partner in a thorough drug safety testing procedure, specializing in histopathology assessments of toxicity and carcinogenicity studies. Global Pathology Support also has ample experience in conducting neuropathology assessments and gross pathology assessments. This laboratory maintains a particular focus on products seeking validated registration for pharmaceutical or industrial use. By remaining fully compliant with the REACH Agreement and all OECD guidelines, Global Pathology Support ensures they always deliver excellent toxicologic pathology services.